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KMID : 1159320140160040605
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Korean Journal of Vision Science
2014 Volume.16 No. 4 p.605 ~ p.617
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Influence of Cycloplegia on Ocular Aberrations in Emmetropes
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Kim Jeong-Mee
Lee Koon-Ja
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Abstract
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Purpose: To assess the influence of cycloplegia on ocular aberrations in emmetropic eyes.
Methods: Forty eyes of 20 emmetropic subjects in their early twenties (; 10 females, 10 males) were enrolled. The subjects’selection criteria were best unaided monocular visual acuity of 20/20 or better. High and low contrast visual acuity (HCVA and LCVA) using ETDRS charts were measured under photopic and mesopic conditions. Ocular lower-order aberrations (LOAs) and higher-order aberrations (HOAs) were measured for 4-mm and 6-mm pupils, using Wavefront Analyzer (KR-1W, Topcon, Japan) under scotopic condition. All measurements were compared before and after cycloplegia with topical installation of 1% tropicamide and 1% cyclopentolate.
Results: Pupil size in scotopic condition was in non-cycloplegia and in cycloplegic condition. For both HCVA and LCVA photopic and mesopic conditions, there was statistically significant difference between non-cycloplegic and cycloplegic conditions (p=0.000). Regarding defocus for a 6-mm pupil, there was a small but statistically significant difference between non-cycloplegic () and cycloplegic () conditions (p=0.037). For ocular HOAs, although the RMS values of all ocular HOAs with cycloplegia increased when compared with non-cycloplegia, there, however, were no significant differences in total HOAs, third-order, fourth-order, coma, and spherical aberration for both 4-mm and 6-mm pupils between the two conditions. We also did not find any significant changes in corneal and internal HOAs between the two non-cycloplegic and cycloplegic conditions. In non-cycloplegic eyes under photopic lighting condition, HCVA was significant correlated with astigmatism (4-mm pupil) and corneal spherical aberration (6-mm pupil). On the other hand, in cycloplegia, LCVA under photopic condition was significant correlated with ocular coma (4-mm pupil) and defocus (6-mm pupil), and LCVA under mesopic conditions was also significant correlated with corneal total HOAs (6-mm pupil) and corneal spherical aberration (6-mm pupil).
Conclusion: We did not find any effects of cycloplegia on ocular HOAs compared with non-cycloplegia. Ocular HOAs in the wavefront aberration measurement may not be directly affected by accommodation in emmetropes.
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KEYWORD
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Emmetrope, Cycloplegia, Ocular aberrations, Accommodation
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